carbonic anhydrases

カタログ番号	製品名	別名	ターゲット
T6781	Benzenesulfonamide	Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide	Carbonic Anhydrase
	Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.		Carbonic Anhydrase
T2134	Dorzolamide hydrochloride	MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,Dorzolamide HCl	Carbonic Anhydrase
	Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water ...		Carbonic Anhydrase
T0782	Benzthiazide	Aquatag,Lemazide,Dihydrex	Carbonic Anhydrase
	Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ...		Carbonic Anhydrase
T61829	Carbonic anhydrase inhibitor 4
	Carbonic anhydrase inhibitor 4 is a photoprobe that inhibits the activity of carbonic anhydrase. It specifically targets human carbonic anhydrases, including hCA I-XIV, with K i values ranging from 640-1166 nM [1].
T35713	N-desethyl Brinzolamide (oxalate)
	N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1It inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively). 1.Kim, C.-Y., Whittington, D.A., Chang...
T79753	HCAIX/XII-IN-8		Carbonic Anhydrase
	hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.7 nM for CA XII. It demonstrates significant inhibitory effi...		Carbonic Anhydrase
T79591	HCA/VEGFR-2-IN-4		VEGFR
	hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/XII and vascular endothelial growth factor receptor 2 (VEGFR...		VEGFR

Compounds

Benzenesulfonamide

T6781

Synonym: Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide

Target: Carbonic Anhydrase

Dorzolamide hydrochloride

T2134

Synonym: MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,Dorzolamide HCl

Target: Carbonic Anhydrase

Benzthiazide

T0782

Synonym: Aquatag,Lemazide,Dihydrex

Target: Carbonic Anhydrase

Carbonic anhydrase inhibitor 4

T61829

Synonym:

Target:

N-desethyl Brinzolamide (oxalate)

Target: Carbonic Anhydrase

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00478	Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Carbonic anhydrase XII (CA XII) is a key mediator of several signaling pathways that are involved in ...
TMPY-02277	Carbonic Anhydrase 7 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family...
TMPK-00524	CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPJ-00701	Carbonic Anhydrase 11 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of ...
TMPK-00283	CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPY-01761	Carbonic Anhydrase 3 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including re...
TMPJ-00283	Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym...
TMPY-01877	CA5A Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of z...
TMPY-02133	Carbonic Anhydrase VB Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, ...
TMPY-01734	CA13 Protein, Human, Recombinant (His)	Human	E. coli
	The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi...